Can you help cure leukemia and lymphoma with stem cell therapy? Gamida Cell: A possible investment case.

Marko Laesseriger, PhD
3 min readDec 12, 2022

NAM-enabled stem cell therapy is a type of medical treatment that involves the use of stem cells in combination with the vitamin B3 derivative nicotinamide (NAM). Stem cells are undifferentiated cells that have the ability to develop into different types of cells or tissues in the body, and they have been used in a variety of medical treatments to repair or replace damaged or diseased cells or tissues.

The use of NAM in stem cell therapy has been shown to have potential benefits. NAM has been found to promote the growth and differentiation of stem cells, which could make them more effective for use in medical treatments. In addition, NAM has also been found to have anti-inflammatory and immune-modulatory effects, which could help to improve the survival and function of transplanted stem cells.

One potential application of NAM-enabled stem cell therapy is in the treatment of hematologic malignancies, such as leukemia and lymphoma. These conditions are caused by the abnormal growth and proliferation of blood cells, and they can be difficult to treat with traditional therapies. The use of stem cells in combination with NAM could potentially improve the efficacy of stem cell transplantation, leading to better outcomes for patients.

Another potential application of NAM-enabled stem cell therapy is in the treatment of tissue damage or degeneration. For example, stem cells could be used to repair damaged heart tissue after a heart attack, or to regenerate damaged nerve tissue in individuals with neurodegenerative diseases. The use of NAM in these treatments could potentially improve the survival and function of transplanted stem cells, leading to better outcomes for patients.

While NAM-enabled stem cell therapy shows promise, there are also potential risks and challenges that need to be considered. One of the key challenges is the potential for stem cells to differentiate into the wrong type of cell or tissue, which could lead to the development of tumors or other adverse effects. Additionally, the use of NAM in stem cell therapy is still relatively new, and more research is needed to fully understand its potential benefits and risks.

Another potential challenge is the ethical issues surrounding the use of stem cells in medical treatments. In some cases, stem cells are derived from human embryos, which raises ethical concerns about the destruction of human life. Additionally, there are also concerns about the potential for stem cells to be used for purposes other than medical treatment, such as in the creation of genetically modified organisms.

Despite these challenges, the potential benefits of NAM-enabled stem cell therapy are significant and could lead to improved treatments for a variety of conditions. Henceforth, Gamida Cell’s Omidubicel being in the third stage of FDA approval seems to have quite some potential. Thus making an investment at the current level very promising.

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Marko Laesseriger, PhD
Marko Laesseriger, PhD

Written by Marko Laesseriger, PhD

Entrepreneur and tech enthusiast. Finance background and PhD in Social Science. Work experience Big4, M&A, IT consulting.

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